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Basic information

CohesinDB ID: CDBP00417032

Locus: chr21-32594251-32594977

Data sourse: GSE67783, GSE72082, GSE86191, ENCSR000BLS, ENCSR153HNT, GSE165895

Cell type: HCT-116, Hep-G2, K-562, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 47%, "5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, HMG20A, HNF1A, ZNF101, FOXA1, SUZ12, RBFOX2, RXRB, KDM3A, TFAP4, HDGF, TSC22D4, ATF3, NFIC, THRB, PRDM1, ATF4, CDX2, TEAD1, ELF1, TRIM28, RBM39, KLF6, SNAI2, RCOR2, ESR1, OCA2, MED26, CTCF, TCF12, EP300, SOX5, GATA6, E2F6, DMAP1, FOXA3, ZNF175, GATAD2A, EHMT2, RBPJ, GTF2F1, PDX1, MLX, MYCN, HHEX, RUNX1T1, TOP2A, ZNF263, MTA2, ZBTB48, ZSCAN5A, GATAD1, DDX5, NBN, SAP130, ARID3A, TBP, HNF4G, ETS1, MYC, SMARCA4, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, ZNF614, XRCC5, IKZF1, MIER3, HNRNPH1, NR2F6, RCOR1, VDR, NR3C1, CEBPB, CREB1, CCAR2, TBL1XR1, ZNF652, GABPB1, ZHX2, MIXL1, TFE3, HDAC2, GATA2, ZNF644, MXD3, DRAP1, ZGPAT, NFIL3, ETV5, THAP11, BCL6, SMC1A, HDAC1, CEBPA, SOX13, ZFX, ERG3, SP5, SMARCC1, MYBL2, RARA, ZNF384, CDK6, GATA4, ARNT, ZNF48, SMAD4, FOS, HMGXB4, SMARCB1, MED1, TEAD3, ZEB1, SCRT2, ZMYM3, U2AF1, SMAD1, ZNF41, RBM22, BCL11A, SP1, NIPBL, HNF4A, ARID2, IKZF5, REST, ZBTB7A, ASH2L, FOXP1, SMC3, STAG1, ETV4, SKI, TRP47, PPARG, FOXA2, CREM, MIER2, WT1, FOXF1, ZBTB33, TCF7, HOXB13, ZKSCAN1, FOXO3, KDM1A, YY1, ZNF580, ZNF19, RELA, SP140, HIF1A, MAX, GATA1, MTA1, CBX2, CEBPG, NR2F2, ZNF512, NR2F1, NEUROG2, ZNF334, MYOD1, ELF3, PHF5A, KAT8, ARID4B, BHLHE40, NFKBIZ, AR, ZNF366, EGR1, ZBTB26, BRD4, JUND, SCRT1, CUX1, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): HUNK,SCAF4,MIS18A,EVA1C,CFAP298,CFAP298-TCP10L,URB1,TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079,

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Deatailed information for cohesin site CDBP00417032