- Basic information
- CohesinDB ID: CDBP00417037
- Locus: chr21-32604431-32605130
-
Data sourse: ENCSR000BLD, GSE86191, GSE105028, ENCSR000ECE, ENCSR153HNT, GSE97394, GSE64758
-
Cell type: H1-hESC, HCT-116, H9-hESC, K-562, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 69%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: SOX2, XBP1, PATZ1, FOXA1, RBFOX2, HDGF, ATF3, CHD7, MORC2, KLF5, ESR1, CTCF, TCF12, EP300, GATA6, E2F6, TEAD4, TFAP2C, GLIS1, NANOG, POU2F2, BRD1, ZNF263, MYCN, RUNX1T1, POU5F1, ZBTB48, ZSCAN5A, STAT1, DUX4, SRF, SP4, TBP, ERG, ASCL1, MYC, SMARCA4, RFX1, KDM4A, RAD21, GRHL3, NR3C1, KMT2A, CREB1, SPI1, HDAC2, GATA2, MXD3, MXI1, SIN3A, ZFX, SMAD3, TET2, BRD9, ARNT, ATF2, PBX3, SP2, CHD1, SNRNP70, MED1, ZEB1, SCRT2, ZNF3, RBM22, USF1, SP1, REST, ASH2L, CTBP2, BCOR, FOXP1, TCF3, SMC3, STAG1, TRP47, ZNF207, FOXA2, RBBP5, PAF1, ZNF600, WT1, BCL3, KDM1A, YY1, RELA, NEUROD1, SP140, ZIC2, TAL1, MAX, GATA1, AGO2, SP7, NCOA3, NEUROG2, TP53, NFKBIZ, AR, PAX3-FOXO1, TAF1, BRD4, SCRT1, JUND, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): URB1,SYNJ1,HUNK,EVA1C,PAXBP1,CFAP298,MIS18A,SCAF4,CFAP298-TCP10L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000156304,
ENSG00000142149,
ENSG00000159055,
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:22775000-22800000~~chr21:32575000-32600000,
chr21:25725000-25750000~~chr21:32600000-32625000,
chr21:31175000-31200000~~chr21:32575000-32600000,
chr21:31700000-31725000~~chr21:32600000-32625000,
chr21:31725000-31750000~~chr21:32575000-32600000,
chr21:31725000-31750000~~chr21:32600000-32625000,
chr21:31780232-31781825~~chr21:32599877-32601833,
chr21:31850000-31875000~~chr21:32575000-32600000,
chr21:31850000-31875000~~chr21:32600000-32625000,
chr21:31865248-31867144~~chr21:32598994-32601796,
chr21:31865272-31867342~~chr21:32599933-32601810,
chr21:31865442-31866981~~chr21:32599635-32601835,
chr21:31975000-32000000~~chr21:32600000-32625000,
chr21:32075000-32100000~~chr21:32600000-32625000,
chr21:32095976-32097575~~chr21:32599358-32601801,
chr21:32275000-32300000~~chr21:32575000-32600000,
chr21:32275000-32300000~~chr21:32600000-32625000,
chr21:32277555-32280325~~chr21:32599877-32601833,
chr21:32277665-32280330~~chr21:32599933-32601810,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32600000-32625000,
chr21:32305431-32307333~~chr21:32600164-32601910,
chr21:32350000-32375000~~chr21:32600000-32625000,
chr21:32359189-32360657~~chr21:32599840-32601900,
chr21:32375000-32400000~~chr21:32575000-32600000,
chr21:32375000-32400000~~chr21:32600000-32625000,
chr21:32383323-32384788~~chr21:32600164-32601910,
chr21:32385843-32387035~~chr21:32599838-32601801,
chr21:32391754-32394231~~chr21:32599840-32601943,
chr21:32391823-32394318~~chr21:32599840-32601900,
chr21:32391849-32394127~~chr21:32599840-32601796,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32400000-32425000~~chr21:32600000-32625000,
chr21:32401983-32404518~~chr21:32600164-32601910,
chr21:32401987-32404521~~chr21:32599840-32601943,
chr21:32402041-32404495~~chr21:32599358-32601801,
chr21:32402043-32404526~~chr21:32599739-32601803,
chr21:32402099-32404537~~chr21:32599842-32601842,
chr21:32402110-32404433~~chr21:32599840-32601900,
chr21:32402112-32404476~~chr21:32599933-32601810,
chr21:32402135-32404476~~chr21:32598994-32601796,
chr21:32402183-32404544~~chr21:32600127-32601810,
chr21:32402211-32404532~~chr21:32599851-32601933,
chr21:32402220-32404493~~chr21:32600085-32601819,
chr21:32402351-32404483~~chr21:32599809-32601807,
chr21:32402421-32404494~~chr21:32599840-32601796,
chr21:32402474-32404277~~chr21:32599132-32601791,
chr21:32402478-32404275~~chr21:32599877-32601833,
chr21:32402531-32404281~~chr21:32600444-32601827,
chr21:32402537-32404397~~chr21:32599838-32601801,
chr21:32402544-32404481~~chr21:32599871-32601809,
chr21:32402553-32404518~~chr21:32599805-32601899,
chr21:32402562-32404219~~chr21:32600440-32601787,
chr21:32402573-32404309~~chr21:32599384-32601896,
chr21:32402578-32404394~~chr21:32599082-32601833,
chr21:32402579-32404271~~chr21:32600154-32601803,
chr21:32402590-32404484~~chr21:32599845-32601920,
chr21:32402599-32404105~~chr21:32599635-32601835,
chr21:32402611-32404103~~chr21:32600122-32601828,
chr21:32402633-32404158~~chr21:32600087-32601774,
chr21:32402649-32404059~~chr21:32600348-32601794,
chr21:32402698-32403972~~chr21:32600504-32601777,
chr21:32412413-32413787~~chr21:32599845-32601920,
chr21:32412745-32415761~~chr21:32598994-32601796,
chr21:32413259-32415823~~chr21:32599838-32601801,
chr21:32413356-32415861~~chr21:32599851-32601933,
chr21:32413407-32415950~~chr21:32599840-32601796,
chr21:32413601-32416113~~chr21:32599842-32601842,
chr21:32413701-32415963~~chr21:32599805-32601899,
chr21:32413909-32415933~~chr21:32599809-32601807,
chr21:32413950-32415829~~chr21:32600085-32601819,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32475000-32500000~~chr21:32575000-32600000,
chr21:32500000-32525000~~chr21:32600000-32625000,
chr21:32600000-32625000~~chr21:32725000-32750000,