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Basic information

CohesinDB ID: CDBP00417047

Locus: chr21-32627737-32628194

Data sourse: GSE50893, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, GM19193, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 61%, "15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NCOA2, FOXA2, POU5F1, TOP2A, SOX2, ZFX, XBP1, GTF2B, DUX4, ZNF317, ZNF30, FOXA1, ZNF770, SP4, HOXB13, PRDM10, ERG, YY1, RELA, ZNF384, MYC, BRG1, GATA4, GRHL3, HIF1A, NKX2-1, NKX3-1, SUPT5H, ZNF143, CDK8, TLE3, NR3C1, NCOA3, ZNF121, SCRT2, PIAS1, ESR1, OCA2, MAFK, BAF155, SPI1, BCL11A, AR, GATA2, ARID1A, BRD4, FOXP1, SMC3, ZNF316

Target gene symbol (double-evidenced CRMs): SYNJ1,PAXBP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086,

eachgene

Deatailed information for cohesin site CDBP00417047