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Basic information

CohesinDB ID: CDBP00417051

Locus: chr21-32645207-32646681

Data sourse: GSE67783, ENCSR000BKV, GSE126634, GSE111913, GSE105028, GSE152721

Cell type: RT-112, HSPC, K-562, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 43%, "4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, NANOG, TRIM25, SMC1A, FOXA2, POU5F1, MYCN, CREM, SOX2, SIN3A, HMGN3, MEIS2, CBX3, WT1, KDM4C, FOXA1, ERG3, ERG2, PBX2, ERG, YY1, RELA, RARA, OGG1, ATF3, MYC, ETS1, CTCFL, CHD7, SP140, RAD21, GRHL3, SOX11, PCGF1, CBFB, ZFP36, NRF1, STAT3, TAL1, NCAPH2, MAX, CHD1, SUPT5H, SMARCB1, RCOR1, ZNF143, KLF4, KLF5, CEBPD, TRIM28, CREB1, VEZF1, ESR1, ZNF334, PHOX2B, KLF16, CTCF, EP300, KLF1, AR, DPF2, RXR, ZBTB7A, REST, CCNT2, EGR1, HEXIM1, TFIIIC, FLI1, HSF1, HNRNPLL, BRD4, ZNF407, BCOR, ILF3, NOTCH3, MAZ, AATF, SMC1, STAG1

Target gene symbol (double-evidenced CRMs): SYNJ1,PAXBP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 365

Number of somatic mutations (non-coding): 73

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086,

eachgene

Deatailed information for cohesin site CDBP00417051