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Basic information

CohesinDB ID: CDBP00417055

Locus: chr21-32658231-32658886

Data sourse: ENCSR167MTG, ENCSR338DUC, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, ENCSR054FKH, ENCSR153HNT

Cell type: HCT-116, Hep-G2, K-562, Liver, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 39%, "5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, HMG20A, XBP1, FOXA1, RXRB, KDM3A, MXD4, TRIM28, RCOR2, CTCF, EP300, SOX5, FOXA3, ZNF175, GATAD2A, RBPJ, EED, MLX, POU2F2, POU5F1, TOP2A, ZNF563, GATAD1, SAP130, ARID3A, TBP, HNF4G, ETS1, HOMEZ, RXRA, XRCC5, ZNF614, MIER3, ZNF667, NR2F6, HNRNPL, CREB1, EZH2, GABPB1, SPI1, ZNF664, MIXL1, HDAC2, ZNF644, MXD3, ZGPAT, NFIL3, ETV5, PTBP1, THAP11, BCL6, SMC1A, CEBPA, SOX13, ZFX, TET2, SP5, RARA, ZNF384, ZNF48, SMAD4, FOS, HMGXB4, TEAD3, CEBPD, SCRT2, ZMYM3, SP1, GSPT2, HNF4A, IKZF5, FOXP1, SMC3, PPARG, MIER2, WT1, ZNF580, KDM1A, YY1, AHR, SP140, MAX, CEBPG, ELF3, PHF5A, KAT8, ARID4B, BHLHE40, NFKBIZ, ZBTB26, HSF1, NOTCH3, BRD4, MAZ, DMAP1

Target gene symbol (double-evidenced CRMs): TMEM50B,SYNJ1,PAXBP1,IFNGR2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 30

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086, ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417055