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Basic information

CohesinDB ID: CDBP00417057

Locus: chr21-32660445-32661444

Data sourse: ENCSR000BLD, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE25021, GSE108869, ENCSR000BTU, ENCSR000EAC, GSE67783, ENCSR000BKV, GSE86191, GSE101921, GSE138105, ENCSR703TNG, GSE94872, ENCSR000BLS, ENCSR000ECE, ENCSR000EHX, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, GSE129526, GSE111913, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE50893, GSE131577

Cell type: GM2610, SLK, GM19240, HuCC-T1, H9-hESC, GM2630, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, H1-hESC, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, MCF-7, GM12892, HCT-116, HL-60, Hep-G2, A-549, HUVEC, HCAEC, GM19238, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 14% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.656

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 47%, "4_Tx": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, RXR, PPARG, NR2F2, EGLN2, GATA2, PIAS1, ASH2L, ARNT, ESR1, HIF1A, SMAD3, NKX2-1, GRHL2, FOXA1, STAT3, MAX, NKX3-1, BAF155

Target gene symbol (double-evidenced CRMs): TMEM50B,PAXBP1,IFNGR2,SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 65

Number of somatic mutations (non-coding): 13

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086, ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417057