- Basic information
- CohesinDB ID: CDBP00417059
- Locus: chr21-32668006-32668064
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 69%,
"4_Tx": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF143, GATA1, MYCN, TOP2A, NCOR1, NOTCH3, XBP1, EED, HIF1A, ZNF528, ERG3, PAX5, ZSCAN4, SUPT5H, ERG, YY1
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2,SYNJ1,PAXBP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159086,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32750000-32775000,
chr21:32650000-32675000~~chr21:32800000-32825000,
chr21:32650000-32675000~~chr21:32825000-32850000,
chr21:32650000-32675000~~chr21:32875000-32900000,
chr21:32650000-32675000~~chr21:32925000-32950000,
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32650000-32675000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:33175000-33200000,
chr21:32650000-32675000~~chr21:33425000-33450000,
chr21:32650000-32675000~~chr21:33450000-33475000,