- Basic information
- CohesinDB ID: CDBP00417061
- Locus: chr21-32682583-32683488
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Data sourse: GSE206145, ENCSR230ZWH, ENCSR879KXD, ENCSR917QNE
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Cell type: K-562, Liver, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 67%,
"15_Quies": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZNF496, SOX2, HNF1A, FOXA1, ATF3, NFIC, CHD7, PRDM1, HNF1B, PITX3, JUN, TCF12, CTCF, BAF155, EP300, MNT, GATA6, DPF2, TEAD4, TFAP2C, NANOG, MYCN, ZNF317, ZBTB48, ERG2, HNF4G, ERG, ASCL1, ONECUT1, MYC, EOMES, SMARCA4, ARID1B, RAD21, GRHL3, RXRA, GABPA, NKX3-1, RCOR1, CEBPB, KMT2A, EBF3, SPI1, IRF1, GATA2, FLI1, SMARCA5, HEXIM1-CDK9, ZIM3, RUNX1, SMC1A, LDB1, ZFX, SMAD3, ERG3, TWIST1, ZNF384, SMAD2, GATA4, SMAD4, HMBOX1, CBFA2T3, SUPT5H, PIAS1, NUP98-HOXA9, BCL11A, SP1, HNF4A, ZBTB7A, ARID1A, HOXA9, PHIP, FOXP1, PRDM6, TRP47, FOXA2, CHD2, ZNF823, HOXB13, YY1, BRG1, ISL1, HIF1A, OTX2, GATA3, TAL1, GATA1, ZNF143, HAND2, TLE3, ZFP69B, NR2F2, PHOX2B, ELF3, T, AR, ZBTB40, ZBTB42, JUND, BRD4
- Target gene symbol (double-evidenced CRMs): SYNJ1,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 45
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159128,
- Related loop:
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32675000-32700000~~chr21:32925000-32950000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33400000-33425000,
chr21:32686727-32688995~~chr21:32825782-32827815,
chr21:32686771-32689009~~chr21:32825818-32827923,
chr21:32687246-32688984~~chr21:32726251-32729172,
chr21:32687246-32688984~~chr21:32825812-32827756,
chr21:32687269-32688980~~chr21:32825841-32827928,
chr21:32687309-32688956~~chr21:32825826-32827775,
chr21:32687321-32688946~~chr21:32825808-32827779,
chr21:32687460-32688668~~chr21:32726790-32728912,
chr21:32687493-32688873~~chr21:32770782-32773207,
chr21:32687503-32689164~~chr21:32825859-32827579,
chr21:32687504-32688956~~chr21:32825998-32827550,
chr21:32687515-32688913~~chr21:32825840-32827525,