- Basic information
- CohesinDB ID: CDBP00417063
- Locus: chr21-32687754-32688589
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE138405, GSE101921, GSE152721, GSE138105, GSE130135, ENCSR703TNG, GSE116344, GSE145327, GSE94872, GSE98367, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, GSE129526, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS
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Cell type: RH4, GM10847, GM2610, SLK, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, THP-1, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 22% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.489
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 59%,
"4_Tx": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, GTF2B, FOXA1, HOXB13, RELA, ZBTB2, ZNF384, ETS1, MYC, RAD21, DAXX, ATF4, GATA3, ATF2, BATF, TAL1, NR2F6, NR2F2, NR2F1, PIAS1, KDM5B, STAG1, TP53, ESR1, ZNF334, CTCF, MAFK, BCL11A, SPI1, MIXL1, GATA2, HSF1, SMC1, SMC3, STAG2, ZNF316
- Target gene symbol (double-evidenced CRMs): SYNJ1,PAXBP1,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 85
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159086,
ENSG00000159128,
- Related loop:
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32675000-32700000~~chr21:32925000-32950000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33400000-33425000,
chr21:32686727-32688995~~chr21:32825782-32827815,
chr21:32686771-32689009~~chr21:32825818-32827923,
chr21:32687246-32688984~~chr21:32726251-32729172,
chr21:32687246-32688984~~chr21:32825812-32827756,
chr21:32687269-32688980~~chr21:32825841-32827928,
chr21:32687309-32688956~~chr21:32825826-32827775,
chr21:32687321-32688946~~chr21:32825808-32827779,
chr21:32687460-32688668~~chr21:32726790-32728912,
chr21:32687493-32688873~~chr21:32770782-32773207,
chr21:32687503-32689164~~chr21:32825859-32827579,
chr21:32687504-32688956~~chr21:32825998-32827550,
chr21:32687515-32688913~~chr21:32825840-32827525,