- Basic information
- CohesinDB ID: CDBP00417070
- Locus: chr21-32702794-32703230
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Data sourse: GSE98367, ENCSR153HNT, GSE165895
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Cell type: K-562, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 52%,
"7_Enh": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SOX2, XBP1, FOXA1, PBX2, ATF3, ZFP64, ZNF362, ZBTB44, PRDM1, ZNF189, MZF1, ZNF629, TEAD1, TRIM28, ETV1, ESR1, HNF1B, OCA2, PITX3, CTCF, TCF12, JUN, BAF155, EP300, GATA6, DPF2, SOX4, E2F1, ZNF528, PDX1, TFAP2C, NANOG, POU2F2, CHD8, MYCN, TOP2A, ZSCAN21, ZBTB17, ERF, ZBTB48, ZNF205, ZNF563, HNF4G, ERG, ZBTB21, ZNF300, ZNF341, MYC, SMARCA4, TSHZ1, ARID1B, EOMES, NKX2-1, GABPA, NKX3-1, RCOR1, ZNF667, ZNF639, NR3C1, CEBPB, CREB1, EZH2, KLF8, FEZF1, EBF3, ZKSCAN5, EHF, HDAC2, GATA2, FLI1, MXI1, HEXIM1-CDK9, MRTFB, RUNX1, SMC1A, NKX2-2, ZNF335, ZFX, SMAD3, ZNF770, ERG3, TWIST1, SMARCC1, PRDM10, ZNF18, ZNF384, ZNF35, RUNX2, CDK6, GATA4, OSR2, ZNF184, SP3, ARNT, PBX4, ZEB2, ZNF518A, ZNF10, SUPT5H, FOS, CDK8, MED1, ZXDB, CEBPD, PIAS1, NUP98-HOXA9, ARID1A, OVOL3, RBM25, POU2F3, ASH2L, PHIP, FOXP1, PRDM6, PPARG, FOXA2, CREM, ZNF600, ZNF692, GTF2B, WT1, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, JUNB, BRG1, HIF1A, GATA3, TAL1, GATA1, ZNF143, TLE3, KLF4, SP7, TP53, ELF3, BRD2, AR, PAX3-FOXO1, ZNF324, ZNF366, HSF1, BRD4, JUND, ZNF440, ZSCAN23, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): URB1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000159082,
- Related loop:
chr21:32375000-32400000~~chr21:32700000-32725000,
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32675000-32700000~~chr21:32925000-32950000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33400000-33425000,
chr21:32700000-32725000~~chr21:32800000-32825000,
chr21:32700000-32725000~~chr21:32850000-32875000,
chr21:32700000-32725000~~chr21:32875000-32900000,