- Basic information
- CohesinDB ID: CDBP00417074
- Locus: chr21-32717971-32718233
-
Data sourse: GSE111537, GSE98367
-
Cell type: OCI-AML-3, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 59%,
"15_Quies": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, ZSCAN5C, ZNF660, SOX2, XBP1, HNF1A, PATZ1, FOXA1, ATF3, NFIC, ZFP64, ZNF362, ZBTB44, PRDM1, ATF4, MECOM, ZNF189, ZNF629, JMJD1C, TEAD1, KLF10, ESR1, MLL, CTCF, ZBTB20, TRIM24, ZNF528, TEAD4, KMT2B, TFAP2C, GLIS1, NANOG, CHD8, ZSCAN5D, ZNF778, ID3, ZSCAN21, ZBTB17, ZBTB48, ERG, ZBTB21, MYC, TSHZ1, RAD21, GRHL3, NKX2-1, GABPA, STAT3, NKX3-1, RCOR1, NR2F6, VDR, CEBPB, STAT5B, KMT2A, CREB1, EZH2, KLF8, FEZF1, GRHL2, ZHX2, SPI1, EHF, GATA2, FLI1, RUNX1, SMC1A, CEBPA, NKX2-2, AFF4, ZFX, SMAD3, ZBTB12, REPIN1, ZNF18, PRDM10, SMARCC1, ZNF35, ZNF384, OSR2, ZNF184, PBX4, ARNT, ATF2, ZEB2, SUPT5H, CDK8, ZXDB, MYB, SCRT2, PIAS1, SETDB1, NUP98-HOXA9, BCL11A, NR4A1, OVOL3, PHIP, PRDM6, ZNF394, SKI, FOXA2, TBL1X, EBF1, ZNF600, ZNF692, GTF2B, WT1, ZNF574, MEF2C, CDK9, ZNF580, HOXB13, RELA, HIF1A, TAL1, ZNF143, GATA1, TLE3, KLF4, SP7, ZNF213, MYOD1, ELF3, BRD2, AR, ZNF324, ZNF366, NOTCH3, SCRT1, BRD4, ZNF24
- Target gene symbol (double-evidenced CRMs): URB1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops