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Basic information

CohesinDB ID: CDBP00417078

Locus: chr21-32732552-32732879

Data sourse: GSE206145, GSE206145-GSE177045

Cell type: MCF-7, HEK293T

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 63%, "4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, NANOG, FOXA2, MTA3, ZSCAN5C, ZNF778, PAF1, ZFX, TEAD4, ZNF317, GTF2B, WT1, ZBTB48, NFATC1, FOXA1, DUX4, NME2, ZBTB33, LEO1, HNF4G, ERG, NEUROD1, NFKB2, ZFP64, RFX1, GR, CHD7, POU5F1, PBX4, HIF1A, ARNT, PRDM1, NKX2-1, RAD21, ZNF534, STAT3, TAL1, TOP2A, GATA1, SUPT5H, AGO2, ZNF143, NR3C1, KLF4, CEBPB, NCOA3, ELF1, TEAD1, GATA4, SCRT2, PIAS1, TEAD3, KDM5B, ESR1, GRHL2, ZNF334, NFKB1, PHOX2B, ELF3, RBM22, TFAP2A, ZNF664, EHF, AR, ZNF257, ARID4B, HDAC2, GATA2, EGLN2, CEBPA, MYNN, NOTCH3, ZNF248, BRD4, PHIP, SCRT1, CLOCK, PRDM6, HEXIM1-CDK9, FOXP1, SMC3, ZZZ3, GATAD2A, TFAP2C

Target gene symbol (double-evidenced CRMs): SON,IFNGR2,SCAF4,DONSON,EVA1C,PAXBP1,CFAP298,GART,IFNAR1,SYNJ1,URB1,CFAP298-TCP10L

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000156304, ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086, ENSG00000142166, ENSG00000159128, ENSG00000159131, ENSG00000159140, ENSG00000159147,

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Deatailed information for cohesin site CDBP00417078