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Basic information

CohesinDB ID: CDBP00417080

Locus: chr21-32757827-32758170

Data sourse: ENCSR153HNT, GSE73207

Cell type: K-562, TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 69%, "5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, HMG20A, SOX2, XBP1, FOXA1, RBFOX2, HNRNPK, ATF3, ZNF362, ZBTB44, PRDM1, CHD7, GLYR1, ZNF189, ZSCAN4, MAF, TEAD1, TRIM28, SAP30, ESR1, OCA2, CTCF, JUN, EP300, BAF155, LMO1, SOX5, GATA6, PAX8, DPF2, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, GLIS1, NANOG, ZNF263, POU5F1, TOP2A, CDK7, RUNX1T1, ZBTB17, ZBTB48, ZSCAN5A, DUX4, SP4, ERG, ASCL1, OGG1, ZNF341, ETS1, MYC, ONECUT1, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, SOX10, NKX3-1, IKZF1, RCOR1, NFE2, ZNF639, ESRRA, KMT2A, EZH2, KLF8, GRHL2, FEZF1, SPI1, HDAC2, GATA2, ZIM3, ZNF554, RUNX1, CEBPA, NKX2-2, SOX13, ZFX, ZNF513, TWIST1, ZNF384, SMAD2, GATA4, OSR2, ZNF184, ARNT, PBX4, DAXX, SOX11, PRDM9, SMAD4, HMBOX1, SUPT5H, FOS, CDK8, MED1, ZXDB, MYB, PIAS1, ZNF22, RBM22, MAFK, SP1, BCL11A, POU2F3, ASH2L, FOXP1, PRDM6, SMC3, ZNF283, PPARG, FOXA2, NFATC1, PAF1, ZNF600, GTF2B, WT1, CDK9, HOXB13, KDM1A, ZNF19, RELA, NEUROD1, JUNB, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, AGO2, ZNF143, HAND2, SP7, NCOA3, TCF7L2, TP53, ZNF334, PHOX2B, T, AR, ZNF366, BRD4, JUND, ZZZ3, FOSL2

Target gene symbol (double-evidenced CRMs): GART,URB1,SYNJ1,PAXBP1,SCAF4,SON,DONSON

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000156304, ENSG00000142207, ENSG00000159082, ENSG00000159086, ENSG00000159131, ENSG00000159140, ENSG00000159147,

eachgene

Deatailed information for cohesin site CDBP00417080