- Basic information
- CohesinDB ID: CDBP00417085
- Locus: chr21-32782022-32783924
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Data sourse: GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE126634, ENCSR000BLY, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE138105, ENCSR703TNG, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR247LSH, ENCSR000EHX, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE131956, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, GSE126990, ENCSR000ECS
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Cell type: MDM, SLK, Liver, RPE, Fibroblast, Ishikawa, HeLa-S3, IMR-90, K-562, GBM39, SK-N-SH, HeLa-Tet-On, HAP1, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 20% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, FOXA2, TOP2A, DUX4, ZNF101, FOXA1, ZNF654, CBX8, GATA4, RAD21, OTX2, SUPT5H, GATA1, CBX2, CEBPB, ZNF506, SCRT2, ESR1, CTCF, BCL11A, ZBTB7A, SCRT1, NFIL3, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:32781484-32783866~~chr21:32825796-32827937,
chr21:32781555-32783879~~chr21:32825805-32827853,
chr21:32781953-32783489~~chr21:32825818-32827753,
chr21:32782012-32783834~~chr21:32825823-32827722,
chr21:32782063-32783530~~chr21:32825910-32827724,
chr21:32782069-32783524~~chr21:32825838-32827744,
chr21:32782107-32783797~~chr21:32825805-32827961,
chr21:32782109-32783791~~chr21:32825782-32827847,
chr21:32782139-32783507~~chr21:32825860-32827784,
chr21:32782221-32783814~~chr21:32825812-32827756,
chr21:32782266-32783476~~chr21:32825782-32827815,