- Basic information
- CohesinDB ID: CDBP00417092
- Locus: chr21-32807381-32809281
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Data sourse: GSE67783, GSE98367, GSE138405, GSE126634, GSE206145, GSE152721, GSE206145-NatGen2015, GSE120943, GSE126990
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Cell type: RPE, Hela-Kyoto, Fibroblast, Monocytes, HSPC, HAP1, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, ZSCAN5D, ZSCAN5C, ZFX, ZNF600, ZNF692, ZBTB17, WT1, ZBTB48, ERG3, CBX8, HOXB13, SMARCC1, PRDM10, ZNF18, ERG, RELA, TARDBP, ZNF35, OGG1, NEUROD1, ZNF341, JUNB, ZNF384, SMARCA4, TSHZ1, ZNF184, OSR2, CHD7, ZNF362, OTX2, NKX2-1, ZNF189, STAT3, ZSCAN4, FOS, MED1, CBX2, ZFP69B, CEBPB, SP7, KLF8, ZIM3, FEZF1, ZNF334, CTCF, JUN, ZNF577, BAF155, ZFP28, AR, ZNF182, ZNF366, FLI1, RNF2, HOXA9, PHIP, TCF3, PRDM6, MRTFB, SMC3, ZNF24
- Target gene symbol (double-evidenced CRMs): TIAM1,URB1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 69
- Number of somatic mutations (non-coding): 0
- Related genes and loops