- Basic information
- CohesinDB ID: CDBP00417094
- Locus: chr21-32813428-32813843
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Data sourse: GSE67783, GSE86191, GSE111913, ENCSR000BMY, ENCSR198ZYJ, GSE83726, GSE116344
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Cell type: RH4, HCT-116, Neurons-H1, GM12878, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, CEBPA, ZNF263, FOXA2, ZNF778, SIN3A, ZFX, MYCN, DUX4, ZBTB48, WT1, FOXA1, ZNF205, ERG3, ERG2, HOXB13, ZFHX2, ERG, RELA, ZNF384, JUNB, SMARCA4, GATA4, RFX1, CHD7, RAD21, GRHL3, BATF, ETV6, MAX, ZNF320, HNRNPH1, MED1, CBX2, TLE3, NR3C1, CEBPB, MYOG, TEAD3, MYB, NEUROG2, ESR1, MYOD1, CTCF, TCF12, BAF155, BCL11A, AR, GATA6, IKZF5, REST, ZBTB7A, IRF4, POU2F3, NOTCH3, RFX3, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): URB1,TIAM1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 7
- Related genes and loops