- Basic information
- CohesinDB ID: CDBP00417095
- Locus: chr21-32818375-32819306
-
Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 76%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RELA, ELF1, TOP2A, NR2F1, ZFX, CHD7, GRHL3, NR2C2, ZBTB48, ZBTB26, ZSCAN16, PRDM9, MAZ, STAT3, CTCF, NR2C1, BCL11A, HNRNPH1, NR2F6
- Target gene symbol (double-evidenced CRMs): PAXBP1,URB1,SYNJ1,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000142207,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:31100000-31125000~~chr21:32800000-32825000,
chr21:31200000-31225000~~chr21:32800000-32825000,
chr21:32375000-32400000~~chr21:32800000-32825000,
chr21:32625000-32650000~~chr21:32800000-32825000,
chr21:32650000-32675000~~chr21:32800000-32825000,
chr21:32700000-32725000~~chr21:32800000-32825000,
chr21:32771496-32773602~~chr21:32819061-32820656,