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Basic information

CohesinDB ID: CDBP00417096

Locus: chr21-32819649-32820186

Data sourse: GSE206145-NatGen2015, GSE165895

Cell type: Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 78%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, EZH2phosphoT487, HOXC5, RELA, JUNB, ATF3, MYC, GATA4, PBX4, GRHL3, NKX2-1, STAT3, FOS, GATA1, RCOR1, MED1, NR3C1, CEBPB, CEBPD, NFKB1, JUN, CTCF, BHLHE40, ZBTB42, FLI1

Target gene symbol (double-evidenced CRMs): URB1,SYNJ1,PAXBP1,TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000142207, ENSG00000159082, ENSG00000159086,

eachgene

Deatailed information for cohesin site CDBP00417096