- Basic information
- CohesinDB ID: CDBP00417101
- Locus: chr21-32831636-32833765
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE98367, GSE138405, GSE126634, GSE129526, GSE111913, GSE155324, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE130135, GSE116344, GSE131606, GSE50893
-
Cell type: MCF-7, Macrophage, RPE, Fibroblast, HCT-116, Hela-Kyoto, HEK293T, Monocytes, RH4, Lymphoblast, RT-112, GM2255, HSPC, K-562, B-cell, HAP1, GM18486, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.789
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 49%,
"14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CBX2, SMARCA4, PRDM1, RNF2, CBX8, TCF12
- Target gene symbol (double-evidenced CRMs): ATP5PO,EVA1C,SMIM11A,TMEM50B,AP000295.1,ITSN1,SYNJ1,CRYZL1,IFNAR1,AP000311.1,IFNGR2,IL10RB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
- Related loop:
chr21:31865202-31867229~~chr21:32825802-32827847,
chr21:32400000-32425000~~chr21:32825000-32850000,
chr21:32650000-32675000~~chr21:32825000-32850000,
chr21:32652383-32654378~~chr21:32825782-32827815,
chr21:32652386-32654426~~chr21:32825831-32827860,
chr21:32652389-32654469~~chr21:32825808-32827779,
chr21:32652409-32654456~~chr21:32825866-32827872,
chr21:32652429-32654433~~chr21:32825838-32827744,
chr21:32652434-32654776~~chr21:32825826-32827775,
chr21:32652483-32654348~~chr21:32825846-32827753,
chr21:32652489-32654409~~chr21:32825799-32827554,
chr21:32652499-32654463~~chr21:32825893-32827718,
chr21:32652522-32654350~~chr21:32825860-32827784,
chr21:32652542-32654360~~chr21:32825800-32827808,
chr21:32652578-32654325~~chr21:32825867-32827535,
chr21:32652587-32654469~~chr21:32825810-32827769,
chr21:32652605-32654451~~chr21:32825841-32827928,
chr21:32652616-32654320~~chr21:32825846-32827910,
chr21:32652635-32654427~~chr21:32825998-32827550,
chr21:32652673-32654332~~chr21:32825859-32827579,
chr21:32652681-32654365~~chr21:32825879-32827591,
chr21:32652689-32654365~~chr21:32825802-32827847,
chr21:32652693-32654360~~chr21:32825812-32827756,
chr21:32652694-32654377~~chr21:32825818-32827923,
chr21:32652697-32654249~~chr21:32825837-32827613,
chr21:32652727-32654348~~chr21:32825866-32827565,
chr21:32652742-32654378~~chr21:32825904-32827533,
chr21:32652754-32654437~~chr21:32825782-32827847,
chr21:32652755-32654212~~chr21:32826064-32827444,
chr21:32652769-32654256~~chr21:32826020-32827524,
chr21:32652778-32654242~~chr21:32826025-32827540,
chr21:32652835-32654360~~chr21:32825859-32827506,
chr21:32652869-32654298~~chr21:32825892-32827470,
chr21:32660370-32661816~~chr21:32825818-32827923,
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32686727-32688995~~chr21:32825782-32827815,
chr21:32686771-32689009~~chr21:32825818-32827923,
chr21:32687246-32688984~~chr21:32825812-32827756,
chr21:32687269-32688980~~chr21:32825841-32827928,
chr21:32687309-32688956~~chr21:32825826-32827775,
chr21:32687321-32688946~~chr21:32825808-32827779,
chr21:32687503-32689164~~chr21:32825859-32827579,
chr21:32687504-32688956~~chr21:32825998-32827550,
chr21:32687515-32688913~~chr21:32825840-32827525,
chr21:32770202-32773460~~chr21:32825782-32827847,
chr21:32770305-32773399~~chr21:32825812-32827756,
chr21:32770782-32773207~~chr21:32826025-32827540,
chr21:32781484-32783866~~chr21:32825796-32827937,
chr21:32781555-32783879~~chr21:32825805-32827853,
chr21:32781953-32783489~~chr21:32825818-32827753,
chr21:32782012-32783834~~chr21:32825823-32827722,
chr21:32782063-32783530~~chr21:32825910-32827724,
chr21:32782069-32783524~~chr21:32825838-32827744,
chr21:32782107-32783797~~chr21:32825805-32827961,
chr21:32782109-32783791~~chr21:32825782-32827847,
chr21:32782139-32783507~~chr21:32825860-32827784,
chr21:32782221-32783814~~chr21:32825812-32827756,
chr21:32782266-32783476~~chr21:32825782-32827815,
chr21:32825000-32850000~~chr21:32925000-32950000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32825000-32850000~~chr21:33000000-33025000,
chr21:32825000-32850000~~chr21:33100000-33125000,
chr21:32825000-32850000~~chr21:33125000-33150000,
chr21:32825000-32850000~~chr21:33150000-33175000,
chr21:32825000-32850000~~chr21:33175000-33200000,
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32825000-32850000~~chr21:33350000-33375000,
chr21:32825000-32850000~~chr21:33375000-33400000,
chr21:32825000-32850000~~chr21:33425000-33450000,
chr21:32825000-32850000~~chr21:33450000-33475000,
chr21:32825000-32850000~~chr21:33600000-33625000,
chr21:32825000-32850000~~chr21:33875000-33900000,
chr21:32825000-32850000~~chr21:34350000-34375000,
chr21:32832056-32833659~~chr21:33196178-33197975,
chr21:32832067-32833668~~chr21:33196209-33197929,
chr21:32832075-32833690~~chr21:33196164-33197927,
chr21:32832170-32834191~~chr21:33126567-33128707,
chr21:32832231-32833433~~chr21:33196199-33197967,
chr21:32832273-32833550~~chr21:33126693-33128257,