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Basic information

CohesinDB ID: CDBP00417102

Locus: chr21-32834854-32835342

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 38%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, SMC1A, FOXA2, MYCN, EBF1, RUNX1T1, RBBP5, ZFX, TEAD4, ZBTB48, FOXA1, ZNF770, CBX8, SUZ12, ERG, YY1, RELA, CHD7, ZNF189, MAX, CBX2, CEBPB, TEAD1, EZH2, GRHL2, ZNF652, CTCF, AR, TAF1, ASH2L, BRD4, MAZ, SMC3, EHMT2

Target gene symbol (double-evidenced CRMs): IFNGR2,TMEM50B,IL10RB,CRYZL1,AP000295.1,SYNJ1,IFNAR1,AP000311.1,ATP5PO,EVA1C,SMIM11A,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000166979, ENSG00000159082, ENSG00000249624, ENSG00000243646, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000205670,

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Deatailed information for cohesin site CDBP00417102