- Basic information
- CohesinDB ID: CDBP00417105
- Locus: chr21-32846527-32846785
-
Data sourse: GSE67783, GSE86191
-
Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"14_ReprPCWk": 62%,
"15_Quies": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: AR, CBX2, HDAC2, CEBPB, EZH2, RNF2, KDM5B, EP300
- Target gene symbol (double-evidenced CRMs): SMIM11A,AP000295.1,ATP5PO,ITSN1,EVA1C,SYNJ1,CRYZL1,AP000311.1,IL10RB,TMEM50B,IFNGR2,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
- Related loop:
chr21:32400000-32425000~~chr21:32825000-32850000,
chr21:32625000-32650000~~chr21:32850000-32875000,
chr21:32650000-32675000~~chr21:32825000-32850000,
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32700000-32725000~~chr21:32850000-32875000,
chr21:32725000-32750000~~chr21:32850000-32875000,
chr21:32825000-32850000~~chr21:32925000-32950000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32825000-32850000~~chr21:33000000-33025000,
chr21:32825000-32850000~~chr21:33100000-33125000,
chr21:32825000-32850000~~chr21:33125000-33150000,
chr21:32825000-32850000~~chr21:33150000-33175000,
chr21:32825000-32850000~~chr21:33175000-33200000,
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32825000-32850000~~chr21:33350000-33375000,
chr21:32825000-32850000~~chr21:33375000-33400000,
chr21:32825000-32850000~~chr21:33425000-33450000,
chr21:32825000-32850000~~chr21:33450000-33475000,
chr21:32825000-32850000~~chr21:33600000-33625000,
chr21:32825000-32850000~~chr21:33875000-33900000,
chr21:32825000-32850000~~chr21:34350000-34375000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32850000-32875000~~chr21:33125000-33150000,
chr21:32850000-32875000~~chr21:33175000-33200000,