- Basic information
- CohesinDB ID: CDBP00417115
- Locus: chr21-32870502-32871650
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 48%,
"15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, CHD8, BRD1, FOXA2, MYCN, ZSCAN5D, POU2F2, SMC1A, ZFX, XBP1, ZBTB17, ZBTB48, WT1, ZSCAN5A, FOXA1, YY1, RELA, ZBTB2, CREBBP, EZH1, MYC, GATA4, SP140, GRHL3, ARNT, GATA3, GABPA, STAT3, ETV6, TAL1, SPIB, GATA1, ZNF143, HNRNPH1, SFPQ, PLAG1, GMEB1, NR3C1, CEBPB, NCOA3, CEBPD, MCM7, EZH2, STAG1, ESR1, OCA2, MYOD1, TRPS1, JUN, CTCF, SPI1, AR, GATA6, PAX3-FOXO1, DPF2, HDAC2, GATA2, NOTCH3, BRD4, MAZ, SMC3, EHMT2, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): PAXBP1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:32625000-32650000~~chr21:32850000-32875000,
chr21:32650000-32675000~~chr21:32875000-32900000,
chr21:32700000-32725000~~chr21:32850000-32875000,
chr21:32700000-32725000~~chr21:32875000-32900000,
chr21:32725000-32750000~~chr21:32850000-32875000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32850000-32875000~~chr21:33125000-33150000,
chr21:32850000-32875000~~chr21:33175000-33200000,