- Basic information
- CohesinDB ID: CDBP00417126
- Locus: chr21-32907895-32908656
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Data sourse: GSE116344, GSE62063
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Cell type: RH4, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, XBP1, FOXA1, PBX2, ZNF274, PRDM1, MITF, TRIM28, MLL, OCA2, USF2, CTCF, BAF155, IRF4, RAD51, TEAD4, ZNF175, MYCN, BRD3, RUNX1T1, ZBTB17, ZBTB48, DUX4, ERG, MYC, ARID1B, GRHL3, GABPA, NKX3-1, CREB1, EZH2, FEZF1, SPI1, GATA2, ZNF766, RUNX1, CEBPA, EZH2phosphoT487, ZFX, POU4F2, PCBP2, PRDM10, ARNT, HMBOX1, CBFA2T3, PBX3, MAFB, SCRT2, PIAS1, SETDB1, USF1, BCL11A, ATF7, ASH2L, FOXP1, FOXA2, MIER2, GTF2B, FOXF1, HOXB13, BCL3, FOXO3, RELA, JUNB, HIF1A, OTX2, TAL1, MAX, GATA1, ZNF143, PLAG1, TLE3, KLF4, BCL11B, NR2F2, ZNF512, TCF7L2, TP53, PKNOX1, ZBTB6, PHOX2B, BRD2, AR, EGR1, ZBTB26, NCOR1, JUND, SCRT1, ILF3, BRD4, ZNF440
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops