- Basic information
- CohesinDB ID: CDBP00417127
- Locus: chr21-32911935-32912474
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Data sourse: GSE67783, GSE86191, GSE138405, GSE110061, GSE129526, GSE105028, ENCSR153HNT, ENCSR000EDE, GSE25021, GSE50893
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Cell type: MCF-7, Hela-Kyoto, HCT-116, HeLa-S3, K-562, HSPC, GM18486, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MEIS2, ZFX, FOXA1, SRF, PBX2, ARID3A, ATF3, CTCFL, RAD21, ARID1B, CBFA2T3, GATA1, DACH1, ESRRA, ZNF512, EZH2, ESR1, CTCF, BCL11A, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): IFNGR2,TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops