- Basic information
- CohesinDB ID: CDBP00417129
- Locus: chr21-32918143-32919135
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Data sourse: GSE116344, GSE126634, GSE152721, ENCSR153HNT
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Cell type: K-562, RH4, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, POU2F2, CHD8, SMC1A, PGR, ZNF263, MYCN, RUNX1T1, POU5F1, NME2, MIER2, ZFX, XBP1, ZBTB48, ZSCAN5A, WT1, FOXA1, SRF, ERG3, TET2, DDX5, PBX2, ZNF549, ZKSCAN1, KDM1A, ERG, RELA, ZBTB2, MIER1, RUNX2, MYC, CTCFL, RAD21, CHD7, SP140, SMC3, GABPA, STAT3, XRCC5, ZNF143, CDK8, GATA1, NR3C1, TEAD3, ZNF416, TRIM28, NR2F2, ETV1, EZH2, TP53, PKNOX1, ESR1, SETDB1, CTCF, SPI1, BCL11A, SP1, AR, REST, GATA2, POU2F3, FLI1, ZBTB26, ASH2L, NOTCH3, BRD4, TCF3, E2F1, SMC1, ZNF280A, TEAD4, HKR1, EHMT2
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32900000-32925000~~chr21:33000000-33025000,
chr21:32900000-32925000~~chr21:33100000-33125000,
chr21:32900000-32925000~~chr21:33175000-33200000,
chr21:32900000-32925000~~chr21:33375000-33400000,
chr21:32900000-32925000~~chr21:33425000-33450000,
chr21:32920781-32922713~~chr21:33126530-33128463,
chr21:32921032-32922590~~chr21:33126606-33128591,
chr21:32921094-32922827~~chr21:33126568-33128575,
chr21:32921102-32922797~~chr21:33126505-33128560,
chr21:32921110-32922482~~chr21:33126613-33128557,
chr21:32921135-32922576~~chr21:33126574-33128587,
chr21:32921135-32922576~~chr21:33196131-33197893,
chr21:32921166-32922522~~chr21:33126076-33128364,
chr21:32921267-32922473~~chr21:33126551-33128322,