Browse_each

Basic information

CohesinDB ID: CDBP00417130

Locus: chr21-32920512-32922573

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE126634, ENCSR000EGW, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE76893, GSE101921, GSE135093, GSE152721, GSE120943, GSE206145-NatGen2015, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR000EEG, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, ENCSR981FDC, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR956LGB, ENCSR944ZCT, GSE131956, GSE110061, GSE129526, ENCSR000HPG, GSE111913, GSE155324, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, GSE126755, ENCSR000ECS, GSE38411

Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, RT-112, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, THP-1, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, HeLa, Neutrophil, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 36% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.344

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 67%, "14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, POU2F2, ZNF316, NKX2-2, EZH2phosphoT487, POU5F1, SOX2, ZFX, TOP2A, CRY1, MYCN, ZBTB48, WT1, STAT1, FOXA1, XBP1, TET2, CBX8, ERG3, ERG2, HOXB13, ZFHX2, ZNF300, PAX6, YY1, RELA, ZNF384, ASCL1, NEUROD1, ETS1, MYC, ATF3, SMARCA4, ZNF362, CDK6, CHD7, SP140, RBBP5, HIF1A, OTX2, NKX2-1, PRDM9, ZNF189, MAX, NKX3-1, ZNF143, HAND2, MED1, CEBPB, SCRT2, EZH2, STAG1, OCA2, KLF9, MYOD1, EGR2, PHOX2B, CTCF, ZNF22, EP300, AR, PAX3-FOXO1, POU2F3, MXI1, BRD4, SCRT1, MAZ, SMC3, MYF5, PDX1, AHR

Target gene symbol (double-evidenced CRMs): IFNGR2,TMEM50B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417130