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Basic information

CohesinDB ID: CDBP00417133

Locus: chr21-32929569-32931312

Data sourse: GSE38395, ENCSR000EAC, GSE67783, ENCSR000BMY, ENCSR153HNT, GSE83726, GSE116344, GSE50893

Cell type: RH4, GM12878, GM12891, hLCL, GM2255, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: NIPBL,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, BMI1, NFIC, RUNX3, PRDM1, CBFB, PAX5, ZNF287, ELF1, BCLAF1, ZNF217, TCF12, GATA6, DPF2, IRF4, RAD51, RBPJ, EED, POU2F2, MTA2, NBN, ARID3A, MYC, RAD21, RXRA, BATF3, GABPA, IKZF1, TERF2, NR3C1, CEBPB, STAT5B, CREB1, EZH2, SPI1, HDAC2, ZSCAN29, SMARCA5, RELB, BCL6, EZH2phosphoT487, TRIM22, ZNF18, MEF2A, ZNF384, ARNT, BACH1, ATF2, FOXM1, ETV6, PML, MYB, ZMYM3, STAT5A, SP1, BCL11A, NIPBL, ATF7, ASH2L, MLLT1, NFATC3, MEF2B, MTA3, RBBP5, CREM, NFATC1, E2F8, ZBED1, GTF2B, MEF2C, TCF7, BCL3, YY1, TARDBP, JUNB, ZFP36, SKIL, OTX2, BATF, GATA1, ZNF143, NR2F1, PKNOX1, TBX21, BHLHE40, ZBTB40, EGR1, IKZF2, BRD4, ZNF24

Target gene symbol (double-evidenced CRMs): TMEM50B,SYNJ1,IFNGR2,IFNAR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159082, ENSG00000142166, ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417133