Browse_each

Basic information

CohesinDB ID: CDBP00417134

Locus: chr21-32931964-32933359

Data sourse: ENCSR000DZP, GSE67783, GSE86191, GSE126634, GSE152721, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE83726, GSE116344, GSE50893, GSE73207

Cell type: GM2630, Fibroblast, HCT-116, RH4, SNYDER, TF-1, GM12878, GM2588, GM2255, HSPC, K-562, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.867

Subunit: SMC3,Rad21,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 39%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, HMGN3, NME2, XBP1, FOXA1, UBTF, TFAP4, HDGF, LYL1, NFIC, RUNX3, CHD7, CBFB, MECOM, SMARCE1, PAX5, JMJD1C, MAF, INTS11, ELF1, BCLAF1, TRIM28, MYOG, LMO2, ESR1, MLL, OCA2, CTCF, TCF12, BAF155, ARID5B, EP300, LMO1, KLF1, E2F6, IRF4, SMC1, TEAD4, RBPJ, EED, JARID2, POU2F2, CHD8, BRD1, MYCN, ZNF263, RUNX1T1, CDK7, MTA2, ZBTB48, STAT1, SRF, DDX5, NBN, ARID3A, ERG2, TBP, ERG, PBX1, ASCL1, ETS1, MYC, SMARCA4, ARID1B, RAD21, NKX2-1, BATF3, GABPA, STAT3, IKZF1, NFE2, TERF2, RCOR1, STAT5B, KMT2A, EZH2, GRHL2, SPI1, HDAC2, GATA2, INTS13, SIX2, FLI1, RELB, MYF5, RUNX1, SMC1A, BCL6, CEBPA, EZH2phosphoT487, LDB1, ZFX, ERG3, ZMIZ1, MEF2A, ZBTB2, ZNF384, RARA, NRF1, ARNT, ETV6, CBFA2T3, CDK8, MED1, TERF1, MYB, PIAS1, VEZF1, L3MBTL2, EVI1, SP1, BCL11A, GSPT2, NR4A1, REST, ZBTB7A, ASH2L, TCF3, MLLT1, STAG1, SKI, CBFA2T2, MTA3, EBF1, CREM, MEIS1, GTF2B, WT1, MEF2C, HOXB13, BCL3, KDM1A, YY1, RELA, NEUROD1, JUNB, SP140, TCF4, OTX2, GATA3, ZNF519, BATF, TAL1, MAX, SPIB, ZNF143, GATA1, GFI1B, NR2F2, ZNF334, MYOD1, ELF3, TBX21, PAX3-FOXO1, TAF1, ZBTB16, EGR1, MYNN, RNF2, IKZF2, BRD4, SCRT1, NOTCH3, MAZ

Target gene symbol (double-evidenced CRMs): SYNJ1,TMEM50B,IFNGR2,IFNAR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159082, ENSG00000142166, ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417134