- Basic information
- CohesinDB ID: CDBP00417140
- Locus: chr21-32955846-32956667
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"13_ReprPC": 37%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, XBP1, FOXA1, SUZ12, PBX2, ZFHX2, BMI1, CHD7, PRDM1, TRIM28, LMO2, ESR1, USF2, CTCF, EP300, KLF1, LMO1, PAX8, RAD51, TEAD4, RBPJ, NANOG, CHD8, POU2F2, ZSCAN5D, POU5F1, MYCN, ID3, ZBTB17, ZBTB48, ZSCAN5A, ERG2, ERG, PBX1, NFKB2, MYC, SMARCA4, RAD21, NKX2-1, GABPA, NFE2, ARNTL, NR3C1, CEBPB, KMT2A, EZH2, HDAC2, INTS13, FLI1, ZIM3, EZH2phosphoT487, ZFX, TET2, CBX8, ERG3, ZNF770, ZNF384, GR, ARNT, ATF2, MED1, ZNF264, MYB, ZNF22, USF1, BCL11A, MAFK, REST, TCF3, SMC3, STAG1, TRP47, PPARG, SS18, WT1, KDM1A, YY1, RELA, NEUROD1, SP140, OTX2, TAL1, NRIP1, GATA1, PLAG1, CBX2, ZNF334, NFKB1, EGR2, AR, ZBTB16, EGR1, RNF2, BRD4, CLOCK, MAZ
- Target gene symbol (double-evidenced CRMs): TMEM50B,AP000295.1,IFNAR1,SYNJ1,IL10RB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33450000-33475000,