- Basic information
- CohesinDB ID: CDBP00417141
- Locus: chr21-32958326-32958988
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Data sourse: GSE86191, GSE111913, GSE101921, GSE68388, GSE116344
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Cell type: MCF-10A, RH4, HCT-116, RT-112, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 40%,
"13_ReprPC": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZNF394, PGR, POU2F2, CBX1, ZSCAN5D, NKX2-2, FOXA2, ZNF263, RUNX1T1, ZFX, STAG2, ZSCAN21, POU5F1, WT1, SMAD3, ZBTB48, FOXA1, ZNF134, CBX8, SUZ12, ERG3, PBX2, HOXB13, KDM1A, ERG, JUNB, ATF3, ZC3H8, GRHL3, HIF1A, ARNT, GATA3, GABPA, DPF1, MAX, PBX3, NKX3-1, ZNF143, FOS, MITF, SP2, ZNF10, GATA1, CBX2, KLF4, CEBPB, MYOG, SCRT2, CREB1, ETV1, EZH2, TP53, ESR1, PKNOX1, GRHL2, ZNF334, SETDB1, MYOD1, ZFP91, USF2, NANOG, USF1, SPI1, ZNF695, GATA2, EGLN2, SIX2, RNF2, BRD4, SCRT1, DDX20, PDX1, FOSL2
- Target gene symbol (double-evidenced CRMs): IFNAR1,AP000295.1,TMEM50B,SYNJ1,IL10RB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33450000-33475000,