- Basic information
- CohesinDB ID: CDBP00417145
- Locus: chr21-32970880-32971243
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 64%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFIA, FOXA2, MYCN, POU5F1, SIN3A, FOXA1, HOXB13, ERG, RELA, ZNF35, AHR, NFIC, BRG1, ARNT, GABPA, NRIP1, NKX3-1, TLE3, TRIM28, SCRT2, CREB1, PIAS1, EZH2, ESR1, PKNOX1, STAT5A, SPI1, BAF155, PAX3-FOXO1, AR, GATA2, ARID1A, BRD4, FOXP1, TFAP2C
- Target gene symbol (double-evidenced CRMs): IFNAR1,TMEM50B,IL10RB,AP000295.1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33450000-33475000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33425000-33450000,