- Basic information
- CohesinDB ID: CDBP00417146
- Locus: chr21-32973939-32974357
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Data sourse: GSE120943, GSE67783, GSE86191
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Cell type: Monocytes, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 53%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CHD8, PPARG, FOXA2, MYCN, EZH2phosphoT487, CEBPA, SOX2, TOP2A, ZNF534, ZNF496, POU5F1, ZFX, WT1, ZNF600, FOXA1, ERG3, CBX8, ERG2, ZFHX2, KDM1A, RELA, ZNF384, ATF3, MYC, GRHL3, ARNT, RXRA, ATF2, ZNF519, BATF, KLF15, GATA3, STAT3, GABPA, NR2F6, MED1, CBX2, KLF4, NR2F2, ELF1, NR2F1, EZH2, ZNF334, EGR2, CTCF, JUN, ELF3, SPI1, KLF1, HNF4A, PAX3-FOXO1, EGR1, ZNF263, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): SYNJ1,IFNAR1,IL10RB,TMEM50B,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33450000-33475000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33425000-33450000,