- Basic information
- CohesinDB ID: CDBP00417148
- Locus: chr21-32976543-32977058
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Data sourse: GSE86191, GSE120943, GSE83726, GSE98367
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Cell type: RH4, HCT-116, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 49%,
"15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, SOX2, NME2, XBP1, FOXA1, SUZ12, ZFHX2, ATF3, NFIC, ZFP64, PRDM1, ZSCAN4, MITF, ZNF736, MYOG, THRAP3, ESR1, MLL, CTCF, TCF12, EP300, PAX8, ZNF512B, PDX1, TFAP2C, RBPJ, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, TOP2A, KDM4C, MTA2, ZBTB48, ZSCAN5A, DDX5, ERG2, TBP, ERG, MYC, MCM5, RAD21, STAT3, APC, IKZF1, ZNF750, EZH2, SPI1, SSRP1, GATA2, GATAD2B, SIX2, FLI1, RUNX1, SMC1A, HDAC1, EZH2phosphoT487, ZFX, TET2, ERG3, ZNF184, ARNT, NFIB, PRDM9, PBX3, GMEB1, SCRT2, KLF9, POU2F3, TCF3, SMC3, STAG1, MLLT1, FOXA2, NFATC1, GTF2B, WT1, ZNF662, CDK9, BCL3, YY1, RELA, ZNF148, MCM3, SP140, HIF1A, MAF1, GATA1, ZNF143, MTA1, KLF4, NCOA3, ZNF512, KDM5B, EGR2, AR, ZNF366, EGR1, HSF1, NCOR1, BRD4, CLOCK, MAZ, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32950000-32975000,
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32850000-32875000~~chr21:32950000-32975000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33450000-33475000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33425000-33450000,