- Basic information
- CohesinDB ID: CDBP00417155
- Locus: chr21-32991381-32992043
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Data sourse: ENCSR404BPV, GSE206145, GSE206145-NatGen2015, ENCSR198ZYJ, GSE68388
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Cell type: RPE, Fibroblast, HEK293T, Neurons-H1, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 47%,
"13_ReprPC": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, POU2F2, CHD8, ZSCAN5D, MYCN, EZH2phosphoT487, ZFX, ZSCAN16, WT1, ZSCAN5A, SMAD3, FOXA1, YY1, RELA, ASCL1, NEUROD1, SMARCA4, RAD21, CHD7, GRHL3, HIF1A, ARNT, OTX2, MED1, ZNF467, NCOA3, ZEB1, EZH2, LMO2, ESR1, TP53, NFKB1, CTCF, ZNF257, NOTCH3, BRD4, SMC3
- Target gene symbol (double-evidenced CRMs): IFNGR2,TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33425000-33450000,
chr21:32993184-32995333~~chr21:33126574-33128599,
chr21:32993207-32995324~~chr21:33126563-33128429,
chr21:32993207-32995324~~chr21:33196243-33197889,
chr21:32993209-32995349~~chr21:33100623-33102113,
chr21:32993209-32995349~~chr21:33126505-33128560,
chr21:32993210-32995186~~chr21:33126569-33128688,
chr21:32993249-32995238~~chr21:33126606-33128591,
chr21:32993264-32995466~~chr21:33126574-33128587,
chr21:32993425-32995195~~chr21:33126574-33128362,
chr21:32993426-32995167~~chr21:33196158-33197940,
chr21:32993440-32995435~~chr21:33126529-33128418,
chr21:32993440-32995435~~chr21:33196275-33197980,
chr21:32993448-32995163~~chr21:33126629-33128592,
chr21:32993453-32995444~~chr21:33126567-33128707,
chr21:32993483-32995508~~chr21:33126530-33128463,
chr21:32993491-32995278~~chr21:33126568-33128575,
chr21:32993494-32995284~~chr21:33126613-33128557,
chr21:32993499-32995155~~chr21:33126713-33128335,
chr21:32993504-32995159~~chr21:33126652-33128492,
chr21:32993506-32995325~~chr21:33126537-33128587,
chr21:32993520-32995460~~chr21:33126551-33128322,
chr21:32993524-32995166~~chr21:33196196-33197944,
chr21:32993555-32995462~~chr21:33196237-33197895,
chr21:32993563-32995166~~chr21:33126563-33128587,
chr21:32993582-32995152~~chr21:33126060-33128582,
chr21:32993595-32995110~~chr21:33126657-33128503,
chr21:32993595-32995110~~chr21:33605287-33606550,
chr21:32993635-32995165~~chr21:33126534-33128328,
chr21:32993646-32995155~~chr21:33126534-33128326,
chr21:32993664-32995444~~chr21:33126650-33128283,
chr21:32993664-32995444~~chr21:33195966-33197950,
chr21:32993690-32995144~~chr21:33196531-33197869,
chr21:32993764-32995256~~chr21:33126722-33128225,