- Basic information
- CohesinDB ID: CDBP00417156
- Locus: chr21-32992487-32996486
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE139435, GSE93080, GSE67783, GSE101921, ENCSR806UKK, GSE51234, GSE120943, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, GSE130140, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE68388, GSE126990
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Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CUTLL1, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, A-549, HUVEC, HCAEC, Ramos, GM19238, HeLa, CNCC-WT33iPSC, TC-71, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 72% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.200
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 56%,
"15_Quies": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYC, EZH2, ARNT, ESR1, GRHL3, XBP1, ERG, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): IFNGR2,TMEM50B,AP000311.1,CRYZL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:32825000-32850000~~chr21:32975000-33000000,
chr21:32825000-32850000~~chr21:33000000-33025000,
chr21:32900000-32925000~~chr21:33000000-33025000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33425000-33450000,
chr21:32993184-32995333~~chr21:33126574-33128599,
chr21:32993207-32995324~~chr21:33126563-33128429,
chr21:32993207-32995324~~chr21:33196243-33197889,
chr21:32993209-32995349~~chr21:33100623-33102113,
chr21:32993209-32995349~~chr21:33126505-33128560,
chr21:32993210-32995186~~chr21:33126569-33128688,
chr21:32993249-32995238~~chr21:33126606-33128591,
chr21:32993264-32995466~~chr21:33126574-33128587,
chr21:32993425-32995195~~chr21:33126574-33128362,
chr21:32993426-32995167~~chr21:33196158-33197940,
chr21:32993440-32995435~~chr21:33126529-33128418,
chr21:32993440-32995435~~chr21:33196275-33197980,
chr21:32993448-32995163~~chr21:33126629-33128592,
chr21:32993453-32995444~~chr21:33126567-33128707,
chr21:32993483-32995508~~chr21:33126530-33128463,
chr21:32993491-32995278~~chr21:33126568-33128575,
chr21:32993494-32995284~~chr21:33126613-33128557,
chr21:32993499-32995155~~chr21:33126713-33128335,
chr21:32993504-32995159~~chr21:33126652-33128492,
chr21:32993506-32995325~~chr21:33126537-33128587,
chr21:32993520-32995460~~chr21:33126551-33128322,
chr21:32993524-32995166~~chr21:33196196-33197944,
chr21:32993555-32995462~~chr21:33196237-33197895,
chr21:32993563-32995166~~chr21:33126563-33128587,
chr21:32993582-32995152~~chr21:33126060-33128582,
chr21:32993595-32995110~~chr21:33126657-33128503,
chr21:32993595-32995110~~chr21:33605287-33606550,
chr21:32993635-32995165~~chr21:33126534-33128328,
chr21:32993646-32995155~~chr21:33126534-33128326,
chr21:32993664-32995444~~chr21:33126650-33128283,
chr21:32993664-32995444~~chr21:33195966-33197950,
chr21:32993690-32995144~~chr21:33196531-33197869,
chr21:32993764-32995256~~chr21:33126722-33128225,
chr21:33000000-33025000~~chr21:33100000-33125000,
chr21:33000000-33025000~~chr21:33125000-33150000,