- Basic information
- CohesinDB ID: CDBP00417163
- Locus: chr21-33010969-33012407
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Data sourse: GSE206145-GSE177045, GSE72082, GSE98367, GSE138405, ENCSR150EFU, GSE206145-NatGen2015, GSE120943, ENCSR000EDE, GSE68388, ENCSR703TNG, GSE126990, GSE126755, ENCSR000ECS, GSE165895
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Cell type: MCF-7, Macrophage, Fibroblast, Hela-Kyoto, Monocytes, A-549, HeLa-S3, Neutrophil, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 62%,
"13_ReprPC": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, ZNF660, SOX2, XBP1, PATZ1, FOXA1, SUZ12, MLL4, ZFHX2, TFAP4, LYL1, INSM2, NFIC, ATF3, SETX, ZNF362, PRDM1, KLF14, ZNF189, SMARCE1, MITF, ZNF320, ZNF736, JMJD1C, ZNF629, TEAD1, TRIM28, ZNF573, KLF10, LMO2, ESR1, MLL, USF2, CTCF, JUN, ZNF507, TCF12, EP300, BAF155, MNT, ZNF157, SOX5, DPF2, SOX4, TRIM24, RFX5, DEK, TEAD4, KMT2B, FOXA3, ZNF175, GATAD2A, EHMT2, TFAP2C, GLIS1, POU2F2, CHD8, ZNF263, MYCN, RUNX1T1, CTBP1, ZSCAN21, ZBTB17, DUX4, ZBTB48, STAT1, SAP130, ERG2, TBP, ERG, ZBTB21, HOXC5, NFKB2, ETS1, MYC, SMARCA4, TSHZ1, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, PROX1, GABPA, STAT3, XRCC5, ZNF398, NFE2, ZNF343, ZNF639, RCOR1, VDR, ARNTL, NR3C1, CEBPB, MIER3, KMT2A, CREB1, EZH2, KLF8, GRHL2, GABPB1, SPI1, TFE3, IRF1, ZNF257, HDAC2, GATA2, INTS13, ZNF644, FLI1, SREBF1, NCOA2, ZNF554, ZIM3, RUNX1, THAP11, SMC1A, CBX1, CEBPA, BCL6, ZNF335, ZFX, FIP1L1, SIN3A, SOX13, SMAD3, ZFP37, CBX8, ERG3, SMARCC1, PRDM10, CREBBP, ZNF35, RARA, ZXDC, RUNX2, GATA4, ZNF184, SP3, PBX4, DAXX, ARNT, ZBTB10, ATF2, ZNF518A, SMAD4, PBX3, ZNF10, FOS, CDK8, SP2, MED1, ZEB1, TEAD3, CEBPD, MYB, ZXDB, ZNF558, STAT5A, USF1, SP1, BCL11A, NIPBL, HNF4A, IKZF5, REST, ATF7, ZNF548, TCF3, FOXP1, SMC3, ELL2, STAG1, ZNF394, SKI, PPARG, FOXA2, TBL1X, ZNF716, ZNF600, ZNF692, MIER2, WT1, MEF2C, CDK9, YY1, RELA, JUNB, NEUROD1, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, GATA1, MTA1, ZNF143, CBX2, TLE3, ZFP69B, SP7, NR2F2, NEUROG2, TCF7L2, KDM5B, TP53, PKNOX1, ZBTB6, ZNF334, NFKB1, ZSCAN22, EGR2, BRD2, ELF3, BHLHE40, AR, ARID4B, RXR, ZNF324, ZNF366, EGR1, ZNF280D, BRD4, JUND, MAZ, ZSCAN23, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops