- Basic information
- CohesinDB ID: CDBP00417171
- Locus: chr21-33039667-33039909
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Data sourse: ENCSR000BLD, GSE116344, GSE120943
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Cell type: H1-hESC, RH4, Monocytes
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 68%,
"15_Quies": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CTNNB1, SMC1A, EZH2phosphoT487, MYCN, CDK7, SOX2, TOP2A, ZFX, POU4F2, POU5F1, ZBTB48, WT1, TET2, PAX6, YY1, ASCL1, NOTCH1, NEUROD1, MYC, SMARCA4, CHD7, SP140, ARNT, NKX2-1, TAL1, MAX, ZNF449, MED1, ZEB1, NEUROG2, EZH2, KLF9, MYOD1, CTCF, TCF12, USF1, SOX4, E2F6, BRD4, TCF3, TEAD4, RBPJ
- Target gene symbol (double-evidenced CRMs): IFNAR1,EVA1C,TMEM50B,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32500000-32525000~~chr21:33025000-33050000,
chr21:32925000-32950000~~chr21:33025000-33050000,
chr21:33025000-33050000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33375000-33400000,
chr21:33025000-33050000~~chr21:33425000-33450000,
chr21:33025000-33050000~~chr21:33450000-33475000,
chr21:33025000-33050000~~chr21:36675000-36700000,
chr21:33025000-33050000~~chr21:36700000-36725000,