- Basic information
- CohesinDB ID: CDBP00417172
- Locus: chr21-33040959-33041685
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Data sourse: ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 53%,
"13_ReprPC": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, ZNF660, XBP1, FOXA1, SUZ12, MLL4, TFAP4, ATF3, NFIC, CHD7, ZNF629, TEAD1, SNAI2, ESR1, OCA2, JUN, CTCF, TCF12, EP300, PAX8, SOX4, E2F1, SMC1, TEAD4, CHD8, ZSCAN5D, MYCN, BRD3, TOP2A, ZBTB17, ZBTB48, ERG, ZBTB21, HOXC5, NFKB2, MYC, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, STAT3, VDR, ARNTL, NR3C1, CEBPB, CREB1, EZH2, ZHX2, SPI1, EHF, GATA2, FLI1, MRTFB, NCOA2, ATF1, SIN3A, ZFX, SMAD3, ZBTB12, ERG3, SMARCC1, PRDM10, ZNF35, RUNX2, SMAD2, GATA4, ZNF184, ARNT, PBX4, SOX11, DAXX, ATF2, HMGB2, SMAD4, ZEB2, PBX3, FOS, CDK8, MED1, ZXDB, ZNF558, SCRT2, USF1, REST, PHIP, SMC3, NCOR2, STAG2, ZNF394, CHD2, ZNF600, ZNF692, WT1, YY1, RELA, JUNB, SP140, ZIC2, OTX2, GATA3, TAL1, MAX, GATA1, ZNF143, KLF4, TCF7L2, TP53, ZNF334, BRD2, AR, TAF1, NOTCH3, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2,IFNAR1,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32500000-32525000~~chr21:33025000-33050000,
chr21:32925000-32950000~~chr21:33025000-33050000,
chr21:33025000-33050000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33375000-33400000,
chr21:33025000-33050000~~chr21:33425000-33450000,
chr21:33025000-33050000~~chr21:33450000-33475000,
chr21:33025000-33050000~~chr21:36675000-36700000,
chr21:33025000-33050000~~chr21:36700000-36725000,