- Basic information
- CohesinDB ID: CDBP00417176
- Locus: chr21-33049543-33050194
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Data sourse: GSE206145, GSE67783
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Cell type: RPE, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 68%,
"13_ReprPC": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, POU5F1, EZH2phosphoT487, ZFX, XBP1, ZBTB48, WT1, FOXA1, TET2, CBX8, RELA, CDK2, RUNX3, SP140, HIF1A, CBX2, EZH2, CTCF, ZBTB7A, HNRNPLL, MAZ, ZNF350, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): EVA1C,IFNAR1,IFNGR2,TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32500000-32525000~~chr21:33025000-33050000,
chr21:32925000-32950000~~chr21:33025000-33050000,
chr21:32925000-32950000~~chr21:33050000-33075000,
chr21:33025000-33050000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33375000-33400000,
chr21:33025000-33050000~~chr21:33425000-33450000,
chr21:33025000-33050000~~chr21:33450000-33475000,
chr21:33025000-33050000~~chr21:36675000-36700000,
chr21:33025000-33050000~~chr21:36700000-36725000,
chr21:33050000-33075000~~chr21:33450000-33475000,