- Basic information
- CohesinDB ID: CDBP00417182
- Locus: chr21-33061664-33062185
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Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE68388
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Cell type: K-562, RPE, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 52%,
"13_ReprPC": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, PBX2, MLL4, KDM3A, TFAP4, LYL1, ATF3, NFIC, RUNX3, CBFB, MECOM, ZNF320, JMJD1C, MYOG, INTS11, MAF, TRIM28, ZNF121, ETV1, LMO2, ESR1, JUN, CTCF, TCF12, EP300, BAF155, LMO1, TRIM24, IRF4, KMT2B, GATAD2A, TFAP2C, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF263, TOP2A, POU5F1, RUNX1T1, CDK7, ZBTB17, ZBTB48, ZSCAN5A, STAT1, MLLT3, ERG, PBX1, OGG1, MYC, RAD21, GRHL3, RXRA, GABPA, STAT3, XRCC5, RCOR1, NFE2, VDR, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, GRHL2, SPI1, IRF1, ZNF257, GATA2, INTS13, FLI1, RUNX1, ZNF585A, SMC1A, CEBPA, EZH2phosphoT487, SIRT6, ZFX, TET2, ERG3, ZNF770, SMARCC1, PRDM10, RARA, ARNT, NRF1, SOX11, FOS, CDK8, MED1, TERF1, CEBPD, MYB, PIAS1, SMAD1, KLF9, NCOA1, EVI1, STAT5A, MAFK, BCL11A, SP1, NR4A1, HNF4A, RBM25, ASH2L, ZNF548, TCF3, FOXP1, AATF, STAG1, MLLT1, SKI, TRP47, MEF2B, TBL1X, MTA3, EBF1, FOXA2, SS18, MEIS1, WT1, MAFF, MEF2C, CDK9, HOXB13, KDM1A, YY1, RELA, SP140, TCF4, OTX2, GATA3, BHLHE22, TAL1, MAX, GATA1, ZNF143, KLF4, ZFP69B, CEBPG, BCL11B, NCOA3, TCF7L2, TP53, PKNOX1, MED, ZNF334, NFKB1, MYOD1, TBX21, AR, PAX3-FOXO1, RXR, ZBTB42, EGR1, HSF1, SCRT1, BRD4, CLOCK, MAZ
- Target gene symbol (double-evidenced CRMs): TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops