- Basic information
- CohesinDB ID: CDBP00417199
- Locus: chr21-33100765-33102031
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Data sourse: GSE93080, GSE67783, ENCSR000BKV, GSE139435, GSE86191, GSE98367, GSE105028, GSE206145-NatGen2015, GSE206145, GSE120943, ENCSR153HNT, GSE103477, GSE131606, GSE50893, GSE126755, GSE131577
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Cell type: MDM, GM10847, H9-hESC, RPE, Fibroblast, GM2255, K-562, GM18486, DKO, GM18526, GM18951, SNYDER, Monocytes, Leukemia-SEM, GM12878, GM12891, GM19239, GM19193, THP-1, Macrophage, GM12892, HCT-116, HL-60, GM19238, Neutrophil, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 50%,
"15_Quies": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, TRIM25, SOX2, FOXA1, SUZ12, LEO1, UBTF, ATF3, CTCFL, CHD7, CBFB, MECOM, PAX5, ZNF736, BACH2, JMJD1C, INTS11, ELF1, TRIM28, LMO2, ESR1, OCA2, CTCF, TCF12, JUN, RYBP, E2F6, TRIM24, KMT2B, RBPJ, TFAP2C, JARID2, POU2F2, CHD8, NANOG, ZSCAN5D, POU5F1, MYCN, RUNX1T1, ZNF263, ZNF317, ZBTB48, ZSCAN5A, ZNF205, ERG2, TBP, ERG, PBX1, OGG1, MYC, SMARCA4, RAD21, GRHL3, STAT3, PRDM14, IKZF1, NFE2, HNRNPH1, CEBPB, KMT2A, CREB1, EZH2, SPI1, INTS13, GATA2, FLI1, NAB2, HCFC1R1, RUNX1, SMC1A, BCL6, CEBPA, EZH2phosphoT487, ZFX, POU4F2, ZNF770, CBX8, ERG3, TET2, RARA, TAF15, NCAPH2, FOS, CDK8, CHD1, MED1, MYB, SCRT2, ZNF3, KLF9, SETDB1, BCL11A, NR4A1, REST, ZBTB7A, HNRNPLL, TCF3, AATF, SMC3, STAG1, SKI, TRP47, TBL1X, FOXA2, EBF1, CREM, WT1, MEF2C, YY1, RELA, TARDBP, NEUROD1, MCM3, SP140, MAX, CBX2, PLAG1, NR2F1, MED, BHLHE40, RXR, EGLN2, TFIIIC, HSF1, RNF2, NOTCH3, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 17
- Related genes and loops