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Basic information

CohesinDB ID: CDBP00417207

Locus: chr21-33121656-33122488

Data sourse: ENCSR000BLD, GSE67783, GSE122299, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE83726

Cell type: RPE, H1-hESC, Fibroblast, HCT-116, RH4, HEK293T, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: NIPBL,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 48%, "15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, RXRB, ZBTB44, IKZF3, ZNF320, ZNF121, LMO2, OCA2, ZNF561, E4F1, SOX5, PAX8, ZNF407, ZNF528, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, CTBP1, STAT1, ZNF485, SAP130, ERG, ZBTB21, EZH1, SMARCA4, RFX1, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, HCFC1, DRAP1, RUNX1, CEBPA, NKX2-2, TET2, ZNF654, TRIM22, SMARCC1, PRDM10, ZBTB2, CBX4, SOX11, ZBTB10, ATF2, SP2, TERF1, SMAD1, EVI1, RBM25, MBD2, CBFA2T2, CBX3, CREM, CHD2, SS18, ZSCAN16, WT1, MEF2C, JUNB, NEUROD1, ZFP36, TCF4, SPIB, ZFP69B, BCL11B, ELF3, ZNF765, ARID4B, EGLN2, HSF1, ZBTB26, SCRT1, ILF3, ADNP, FOSL1, ZNF660, XBP1, PBX2, ATF3, ZC3H8, ZFP64, RUNX3, CBFB, ZNF467, JMJD1C, MYOG, ELF1, RBM39, CTCF, JUN, LMO1, MNT, DPF2, RYBP, IRF4, DDX20, ZNF350, ZNF280A, PDX1, TFAP2C, RBPJ, ZSCAN21, ZBTB17, ZBTB48, ZNF317, NONO, SRF, PBX1, KDM4A, HOMEZ, ZNF2, NKX3-1, PRDM14, MIER3, VDR, NR3C1, TBL1XR1, SMARCA5, NFIL3, CC2D1A, ZBTB24, EZH2phosphoT487, LDB1, SOX13, ZNF770, ARNT, ZNF48, ZEB2, NFYA, PBX3, HMGXB4, TEAD3, DIDO1, ZXDB, USF1, SP1, BCL11A, ATF7, ASH2L, SMC3, MLLT1, STAG1, STAG2, ZNF394, MTA3, EBF1, MEIS1, ZNF580, KDM1A, BRG1, PCGF1, GATA3, TAL1, NRIP1, ZNF143, CBX2, ZNF768, TP53, ZSCAN22, BRD2, PHF5A, KAT8, ARRB1, EGR1, RB1, RNF2, BRD4, JUND, CUX1, PGR, SOX2, PATZ1, RING1B, SIN3B, BMI1, CHD7, ZNF444, ZNF189, MZF1, NFE2L2, ZNF217, ESR1, ZNF524, E2F6, TRIM24, GLIS1, POU2F2, ASH1L, ZSCAN5A, ERG2, SP4, TBP, HNF4G, ETS1, MYC, NKX2-1, GABPA, STAT3, IKZF1, EZH2, SPI1, HDAC2, ZNF182, NFYB, ZNF554, ZNF76, ETV5, BCL6, SIN3A, ERG3, RARA, NFYC, ZNF384, ZNF35, HMGB2, SMAD4, ZNF518A, CDK8, ZMYM3, MAFK, HNF4A, REST, BCOR, FOXP1, PPARG, TBL1X, ZNF692, ZNF30, ZNF574, RELA, TARDBP, MAX, GFI1B, NR2F1, TCF7L2, KDM5B, NEUROG2, PKNOX1, MYOD1, T, AR, ZNF324, AHR, FOSL2, ZSCAN5C, E2F7, SUZ12, LYL1, NFIC, CTCFL, ZNF629, TRIM28, BCLAF1, ETV1, RCOR2, MLL, ZFP91, TCF12, BAF155, EP300, SMC1, TEAD4, EHMT2, EED, CHD8, MYCN, RUNX1T1, ARID3A, ZNF300, ASCL1, ZNF341, RAD21, GRHL3, APC, ZNF614, XRCC5, NFE2, ZNF639, ZNF750, JMJD6, FEZF1, TRPS1, TFE3, IRF1, ZGPAT, ZNF766, MRTFB, ATF1, CBX1, SMC1A, ZFX, SMAD3, CBX8, IRF2, NOTCH1, RUNX2, CDK6, ZSCAN30, OSR2, ZNF184, GATA4, FOS, MED1, MYB, ZNF3, L3MBTL2, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, FOXA2, MIER2, ZNF600, FOXF1, CDK9, HOXB13, YY1, ZNF148, SP140, HIF1A, OTX2, BHLHE22, GATA1, CEBPG, SP7, NCOA3, NR2F2, BHLHE40, ZBTB42, CLOCK, MAZ, ZNF440

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00417207