- Basic information
- CohesinDB ID: CDBP00417213
- Locus: chr21-33139059-33140508
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Data sourse: GSE67783, GSE86191, GSE105028, ENCSR153HNT, GSE116344, GSE50893
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Cell type: HCT-116, RH4, GM12878, GM12890, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 49%,
"13_ReprPC": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: XBP1, ATF3, CBFB, ZNF189, MECOM, TP63, OCA2, MED26, CTCF, EP300, LMO1, E2F6, IRF4, ZNF674, POU2F2, ZNF425, BRD1, POU5F1, MYCN, CDK7, ZNF263, KDM4C, ZBTB48, ZSCAN5A, ERG, ASCL1, OGG1, ETS1, MYC, SMARCA4, RAD21, GRHL3, GABPA, STAT3, XRCC5, EZH2, ZNF664, FLI1, NCOA2, RUNX1, SMC1A, BCL6, EZH2phosphoT487, SIN3A, ZFX, CBX8, RARA, ARNT, PRDM9, FOS, CDK8, MED1, MYB, ZMYM3, L3MBTL2, BCL11A, RBM25, POU2F3, PHIP, AATF, SMC3, STAG1, TRP47, TBL1X, SS18, WT1, CDK9, KDM1A, YY1, RELA, SP140, ZFP36, HIF1A, MGA, MAX, SPIB, ZNF143, CBX2, NCOA3, TP53, AR, RXR, TFIIIC, HSF1, RNF2, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000159082,
- Related loop:
chr21:32625000-32650000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:33125000-33150000,
chr21:32825000-32850000~~chr21:33125000-33150000,
chr21:32850000-32875000~~chr21:33125000-33150000,
chr21:32925000-32950000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:33000000-33025000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33125000-33150000,