- Basic information
- CohesinDB ID: CDBP00417215
- Locus: chr21-33149149-33149999
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 50%,
"13_ReprPC": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PPARG, TBL1X, EZH2phosphoT487, POU5F1, SOX2, ZFX, ZNF621, XBP1, WT1, ZBTB48, FOXA1, TET2, SUZ12, PRDM10, KDM1A, ERG, RELA, ZNF384, ASCL1, NEUROD1, MYC, SMARCA4, ZBTB5, SP140, GRHL3, NKX2-1, OTX2, GABPA, MAX, ZNF143, MED1, CBX2, CEBPB, ZEB1, SCRT2, EZH2, TP53, KLF9, ZNF334, ZSCAN22, CTCF, BAF155, EP300, AR, IRF1, HDAC2, ZNF324, ZNF182, POU2F3, HSF1, BRD4, SCRT1, FOXP1, CLOCK, MAZ, AATF, ZNF554, STAG1, EED
- Target gene symbol (double-evidenced CRMs): SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops
- Related gene:
ENSG00000159082,
- Related loop:
chr21:32625000-32650000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:33125000-33150000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32825000-32850000~~chr21:33125000-33150000,
chr21:32825000-32850000~~chr21:33150000-33175000,
chr21:32850000-32875000~~chr21:33125000-33150000,
chr21:32925000-32950000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:33000000-33025000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33125000-33150000,