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Basic information

CohesinDB ID: CDBP00417216

Locus: chr21-33152273-33153023

Data sourse: GSE206145, GSE67783, GSE86191

Cell type: RPE, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 36%, "13_ReprPC": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, KDM4B, FOXA1, SUZ12, PBX2, UBTF, ATF3, THAP1, CBFB, TP63, JMJD1C, TEAD1, TRIM28, RBM39, LMO2, OCA2, JUN, CTCF, SOX4, E2F6, PDX1, TFAP2C, EED, JARID2, POU2F2, POU5F1, MYCN, TOP2A, ZNF263, ZBTB48, ZSCAN5A, ERG, OGG1, MYC, SMARCA4, RAD21, GRHL3, STAT3, XRCC5, TERF2, EZH2, GRHL2, SPI1, FLI1, PTBP1, RUNX1, SMC1A, CEBPA, EZH2phosphoT487, NKX2-2, SIRT6, ZFX, POU4F2, TET2, ERG3, ARNT, ZNF48, MAFB, MED1, TEAD3, EVI1, BCL11A, REST, ASH2L, HNRNPLL, TCF3, BCOR, AATF, SMC3, STAG1, TRP47, FOXA2, MEIS1, WT1, CDK9, FOXO3, YY1, RELA, NEUROD1, MCM3, SP140, HIF1A, OTX2, TAL1, MAX, ZNF143, GATA1, CBX2, NR2F2, NR2F1, NEUROG2, ZNF334, AR, RXR, HEXIM1, HSF1, NOTCH3, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000159082,

eachgene

Deatailed information for cohesin site CDBP00417216