- Basic information
- CohesinDB ID: CDBP00417217
- Locus: chr21-33153578-33153936
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 56%,
"13_ReprPC": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: XBP1, KDM4B, FOXA1, SUZ12, PBX2, UBTF, ATF3, THAP1, CBFB, TP63, JMJD1C, TEAD1, TRIM28, RBM39, LMO2, OCA2, JUN, CTCF, SOX4, E2F6, PDX1, TFAP2C, EED, JARID2, POU2F2, POU5F1, MYCN, TOP2A, ZNF263, ZBTB48, ZSCAN5A, ERG, OGG1, MYC, SMARCA4, RAD21, GRHL3, STAT3, XRCC5, TERF2, EZH2, GRHL2, SPI1, FLI1, PTBP1, RUNX1, SMC1A, CEBPA, EZH2phosphoT487, NKX2-2, SIRT6, ZFX, POU4F2, TET2, ERG3, ARNT, ZNF48, MAFB, MED1, TEAD3, EVI1, BCL11A, REST, ASH2L, HNRNPLL, TCF3, BCOR, AATF, SMC3, STAG1, TRP47, FOXA2, MEIS1, WT1, CDK9, FOXO3, YY1, RELA, NEUROD1, MCM3, SP140, HIF1A, OTX2, TAL1, MAX, ZNF143, GATA1, CBX2, NR2F2, NR2F1, NEUROG2, ZNF334, AR, RXR, HEXIM1, HSF1, NOTCH3, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159082,
- Related loop:
chr21:32625000-32650000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:33125000-33150000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32825000-32850000~~chr21:33125000-33150000,
chr21:32825000-32850000~~chr21:33150000-33175000,
chr21:32850000-32875000~~chr21:33125000-33150000,
chr21:32925000-32950000~~chr21:33125000-33150000,
chr21:32950000-32975000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33125000-33150000,
chr21:32975000-33000000~~chr21:33150000-33175000,
chr21:33000000-33025000~~chr21:33125000-33150000,
chr21:33025000-33050000~~chr21:33125000-33150000,