- Basic information
- CohesinDB ID: CDBP00417223
- Locus: chr21-33168880-33169528
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Data sourse: GSE111913, GSE67783, GSE86191
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Cell type: RT-112, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 54%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, FOXA1, SUZ12, PBX2, NFIC, PRDM1, ZNF189, TP63, TRIM28, ESR1, TP73, USF2, CTCF, JUN, EP300, MNT, IRF4, KMT2B, PDX1, ZSCAN5D, MYCN, KDM4C, ZBTB48, DUX4, STAT1, ZBTB21, PBX1, ZNF341, MYC, SMARCA4, RFX1, GRHL3, GABPA, XRCC5, IKZF1, RCOR1, NR3C1, SRSF3, EZH2, ZNF436, SPI1, ZNF786, IRF1, INTS13, HCFC1R1, NFYB, ZIM3, SMC1A, NKX2-2, EZH2phosphoT487, ZFX, ZNF534, ZNF770, TET2, CBX8, IRF2, ARNT, ZEB2, PBX3, MAFB, FOS, CDK8, MED1, ZEB1, ZNF250, MYB, L3MBTL2, STAT5A, USF1, SP1, BCL11A, HNF4A, POU2F3, SMC3, STAG1, PAX7, FOXA2, ZSCAN16, GTF2B, WT1, ZBTB33, CDK9, KDM1A, YY1, RELA, NEUROD1, MCM3, SP140, TCF4, HIF1A, ZFP36, ZIC2, BHLHE22, OTX2, TAL1, MAX, SPIB, ZNF143, GATA1, PLAG1, CBX2, NR2F1, PKNOX1, ZBTB6, ZNF334, BRD2, T, AR, RNF2, NOTCH3, BRD4, JUND, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops