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Basic information

CohesinDB ID: CDBP00417226

Locus: chr21-33176533-33177231

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145-NatGen2015, ENCSR153HNT, GSE116344

Cell type: MCF-7, Fibroblast, HCT-116, RH4, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 58%, "15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, ZSCAN5D, EZH2phosphoT487, POU5F1, TOP2A, ZFX, XBP1, WT1, ZSCAN5A, ZBTB48, DUX4, ERG3, SUZ12, CBX8, RELA, GRHL3, TP63, SP2, NKX3-1, IKZF1, CBX2, CREB1, EZH2, ESR1, ZNF41, SPI1, PAX8, RNF2, CLOCK, ZNF528, ZNF623, SMC3

Target gene symbol (double-evidenced CRMs): IFNGR2,CRYZL1,EVA1C,AP000311.1,SYNJ1,TMEM50B,IFNAR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000166979, ENSG00000159082, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000249209, ENSG00000205758,

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Deatailed information for cohesin site CDBP00417226