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Basic information

CohesinDB ID: CDBP00417230

Locus: chr21-33183559-33184328

Data sourse: GSE86191, ENCSR703TNG, ENCSR153HNT, GSE72082

Cell type: K-562, MCF-7, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 52%, "15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, POU2F2, ZNF263, MYCN, RUNX1T1, SIN3A, ZFX, CRY1, POU4F2, GTF2B, ZBTB48, FOXA1, PBX2, ERG, YY1, RELA, CREBBP, AHR, MYC, MCM3, SP140, GRHL3, HIF1A, ARNT, GATA3, PRDM9, ATF2, SMC3, GABPA, NRIP1, GATA1, MITF, NR3C1, ESRRA, NCOA3, TEAD1, NR2F2, CREB1, SCRT2, PIAS1, EZH2, ZNF217, ESR1, STAG1, JUN, CTCF, SPI1, AR, ZNF257, GATA2, IRF4, SCRT1, BRD4, ZNF623, NCOA2, PDX1, TFAP2C

Target gene symbol (double-evidenced CRMs): IFNGR2,EVA1C,IFNAR1,AP000311.1,TMEM50B,CRYZL1,SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000166979, ENSG00000159082, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000249209, ENSG00000205758,

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Deatailed information for cohesin site CDBP00417230