- Basic information
- CohesinDB ID: CDBP00417232
- Locus: chr21-33185475-33185847
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 49%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, POU2F2, CHD8, MYCN, EBF1, RUNX1T1, ZFX, POU4F2, XBP1, ZBTB17, ZBTB48, WT1, ZSCAN5A, STAT1, FOXA1, CDK9, ZNF596, PRDM10, KDM1A, YY1, RELA, ERG, PBX1, LYL1, ETS1, MYC, EZH1, SP140, ZFP36, ZNF48, GATA3, GABPA, TAL1, MAX, ZNF143, MED1, NR3C1, MAF, NR2F2, TRIM28, MYB, STAT5B, ZMYM3, TERF1, EZH2, LMO2, CTCF, TCF12, SP1, SPI1, TBX21, LMO1, PAX8, GATA2, FLI1, ZNF605, BRD4, TCF3, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): IFNGR2,EVA1C,TMEM50B,IFNAR1,CRYZL1,AP000311.1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000159082,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:32400000-32425000~~chr21:33175000-33200000,
chr21:32650000-32675000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32825000-32850000~~chr21:33175000-33200000,
chr21:32850000-32875000~~chr21:33175000-33200000,
chr21:32900000-32925000~~chr21:33175000-33200000,
chr21:32925000-32950000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:33175000-33200000~~chr21:33350000-33375000,
chr21:33175000-33200000~~chr21:33425000-33450000,
chr21:33175000-33200000~~chr21:33600000-33625000,